AOD-9604 is a synthetic peptide fragment derived from the C-terminal region of human Growth Hormone (hGH amino acids 177–191), modified with an additional N-terminal tyrosine residue to enhance stability. Formulated as a high-purity lyophilized powder, AOD-9604 is extensively studied in laboratory research settings evaluating lipolytic pathways, lipid metabolism, adipogenesis inhibition, and cartilage repair mechanisms.
Key Product Specifications
| Specification | Details |
| Product Name | AOD-9604 (Tyr-hGH Fragment 177-191) |
| Quantity | 2mg / 5mg / 10mg per vial |
| Purity | $\ge 98\%$ (HPLC verified) |
| Form | Sterile, lyophilized white powder |
| CAS Number | 221231-10-3 |
| Molecular Formula | $\text{C}_{78}\text{H}_{123}\text{N}_{23}\text{O}_{23}\text{S}_2$ |
| Molecular Weight | 1815.10 g/mol |
| Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe |
Product Highlights & Scientific Context
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Targeted Lipolytic Mechanism: Designed to isolate the fat-metabolizing actions of full-length human growth hormone without interacting with insulin signaling or affecting blood glucose levels in cellular models.
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Modified C-Terminal Fragment: The addition of a terminal tyrosine residue and a disulfide bridge between $\text{Cys}^7$ and $\text{Cys}^{14}$ increases metabolic stability against enzymatic breakdown.
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Non-Diabetogenic Profile: In vitro studies demonstrate that AOD-9604 stimulates lipolysis and inhibits lipogenesis without inducing IGF-1 elevation or altered insulin sensitivity.
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Vacuum Lyophilized: Sealed under nitrogen in glass vials to preserve peptide structure and maximize storage life.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C protected from light and moisture for optimal long-term stability. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with sterile Bacteriostatic Water or saline, store at 2°C – 8°C and use within 30 days. Avoid repeated freeze-thaw cycles.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or cosmetic applications. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.







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