MT-1 (Melanotan-1 / Afamelanotide) is a synthetic peptide analog of the naturally occurring $\alpha$-melanocyte-stimulating hormone ($\alpha$-MSH). Formulated at a high-purity 10mg lyophilized dose, MT-1 is widely utilized in laboratory research examining melanocortin receptor activation, melanogenesis, cellular signaling pathways, and UV radiation response mechanisms.
Key Product Specifications
| Specification | Details |
| Product Name | MT-1 (Melanotan-1 / Afamelanotide) |
| Quantity | 10mg per vial |
| Purity | $\ge 98\%$ (HPLC verified) |
| Form | Sterile, lyophilized white powder |
| CAS Number | 75921-69-6 |
| Molecular Formula | $\text{C}_{78}\text{H}_{111}\text{N}_{21}\text{O}_{19}$ |
| Molecular Weight | 1646.85 g/mol |
| Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
Product Highlights & Scientific Context
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Selective Receptor Affinity: MT-1 functions primarily as an agonist at the Melanocortin-1 receptor (MC1R), providing a stable model for investigating intracellular cAMP signaling and pigment synthesis in melanocyte models.
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High Chemical Stability: Engineered as a linear derivative with structural modifications (including D-Phe and Norleucine substitutions) that enhance half-life and enzymatic stability relative to endogenous $\alpha$-MSH.
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Lyophilized for Longevity: Vacuum-sealed in sterile glass vials to ensure optimal long-term integrity and shelf-life prior to reconstitution.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C away from light and moisture for maximum stability. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with bacteriostatic water or sterile saline, store at 2–8°C and use within 30 days. Avoid repeated freeze-thaw cycles.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or cosmetic applications. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.







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