DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring well-characterized neuropeptide composed of 9 amino acids. Originally isolated from cerebral venous blood in sleep-induced mammalian models, DSIP is supplied as a high-purity 5mg lyophilized dose. In scientific laboratory settings, it is widely investigated for its role in regulating slow-wave (delta) sleep patterns, neuroendocrine stress responses, endocrine secretion rhythms (ACTH and LH release), and antioxidant defense mechanisms.
Key Product Specifications
| Specification | Details |
| Product Name | DSIP (Delta Sleep-Inducing Peptide / Emideltide) |
| Quantity | 5mg per vial |
| Purity | $\ge 98\%$ (RP-HPLC verified) |
| Form | Sterile, lyophilized white powder |
| CAS Number | 62568-57-4 |
| Molecular Formula | $\text{C}_{35}\text{H}_{48}\text{N}_{10}\text{O}_{15}$ |
| Molecular Weight | $848.81\text{ g/mol}$ |
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
Product Highlights & Scientific Context
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Sleep & Circadian Rhythm Modeling: Primary model in neurobiological research examining slow-wave electroencephalogram (EEG) enhancements and sleep architecture modulation.
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Neuroendocrine Regulation: Extensively evaluated for its ability to modulate adrenocorticotropic hormone (ACTH) production and basal cortisol stress responses under physiological stress protocols.
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Central Nervous System Stability: Crosses the blood-brain barrier via passive diffusion and specialized transport systems, making it a valuable target for central signaling assays.
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Vacuum Lyophilized Integrity: Sealed in sterile borosilicate glass vials under nitrogen flush to preserve secondary structure and chemical stability.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C protected from light and moisture for maximum shelf life. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with Bacteriostatic Water or sterile saline, store at 2°C – 8°C and use within 30 days. Avoid repeated freeze-thaw cycles.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or cosmetic applications. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.
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