Ipamorelin is a synthetic pentapeptide and selective ghrelin/growth hormone secretagogue receptor (GHS-R) agonist. Formulated as a high-purity 10mg lyophilized cake, Ipamorelin is one of the most selective growth hormone secretagogues studied in laboratory research settings. It is widely evaluated for its capacity to stimulate pulsatile growth hormone (GH) release from the anterior pituitary without triggering significant baseline spikes in cortisol, prolactin, or appetite-stimulating hormones.
Key Product Specifications
| Specification | Details |
| Product Name | Ipamorelin |
| Quantity | 10mg per vial |
| Purity | $\ge 98\%$ (RP-HPLC & Mass Spectrometry verified) |
| Form | Sterile, lyophilized white powder |
| CAS Number | 170851-70-4 |
| Molecular Formula | $\text{C}_{38}\text{H}_{49}\text{N}_9\text{O}_5$ |
| Molecular Weight | $711.85\text{ g/mol}$ |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
Product Highlights & Scientific Context
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High Receptor Selectivity: Highly targeted agonist at the ghrelin/GHS-R1a receptor, enabling growth hormone release assays while avoiding secondary stimulation of ACTH, cortisol, or prolactin secretion.
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Pulsatile Secretion Profile: Mimics natural physiological growth hormone pulses, making it a primary model in long-term pituitary axis, somatopause, and cellular longevity studies.
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GHRH Synergism: Frequently paired in dual secretagogue research protocols alongside GHRH analogs (such as CJC-1295 No DAC) to examine synergistic somatotroph signaling and elevated IGF-1 gene expression.
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High Chemical Stability: Features C-terminal amidation and D-amino acid substitutions that enhance enzymatic resistance against plasma peptidases.
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Aseptic Lyophilization: Vacuum-sealed under nitrogen in glass vials to preserve molecular structure and guarantee long shelf-life prior to laboratory reconstitution.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C protected from light and moisture for up to 2 years. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with Bacteriostatic Water or sterile saline, store strictly at 2°C – 8°C and use within 28–30 days. Avoid repeated freeze-thaw cycles.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or cosmetic applications. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.
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