GHK-Cu (Copper Tripeptide-1) is a naturally occurring human plasma tripeptide ($\text{Gly-His-Lys}$) complexed with a divalent copper ion ($\text{Cu}^{2+}$). Formulated at a high-concentration 100mg lyophilized cake, GHK-Cu is distinctively recognized by its deep blue hue. It is widely investigated in biomedical and dermatological research for its role in gene expression regulation, collagen and elastin synthesis, extracellular matrix remodeling, anti-inflammatory pathways, and tissue repair dynamics.
Key Product Specifications
| Specification | Details |
| Product Name | GHK-Cu (Copper Tripeptide-1 / Glycyl-L-histidyl-L-lysine copper) |
| Quantity | 100mg per vial |
| Purity | $\ge 98\%$ (RP-HPLC verified) |
| Form | Sterile, lyophilized blue powder |
| CAS Number | 89030-95-5 |
| Molecular Formula | $\text{C}_{14}\text{H}_{24}\text{CuN}_6\text{O}_4$ |
| Molecular Weight | 403.93 g/mol |
| Sequence | Gly-His-Lys (Copper Ion Complex) |
Product Highlights & Scientific Context
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Extracellular Matrix Remodeling: Extensively studied in dermal models for stimulating dermal fibroblast proliferation and upregulating Type I collagen, glycosaminoglycans (GAGs), and decorin.
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Gene Expression Modulation: Research demonstrates GHK-Cu’s ability to reset gene expression patterns toward a healthier, younger state, influencing over 4,000 human genes associated with tissue repair and antioxidant signaling.
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Antioxidant & Anti-Inflammatory Signaling: Acts as a potent quencher of toxic lipid peroxidation products and suppresses pro-inflammatory cytokines like TNF-$\alpha$ and IL-6 in cellular assays.
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High-Concentration 100mg Format: Calibrated specifically for high-throughput laboratory protocols, multi-assay trials, or extended topical/cosmetic formulation testing.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C protected from light and moisture for maximum shelf life. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with Bacteriostatic Water, sterile water, or appropriate buffer, store at 2°C – 8°C and use within 30 days. Protect from direct light.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or direct cosmetic application without proper formulation. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.
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