GLP-3 R (10mg) (frequently referenced in research catalogs as research-grade Retatrutide / triple hormone receptor agonist) is a synthetic multi-target peptide engineered for cutting-edge metabolic research. Formulated as a 10mg lyophilized cake, GLP-3 R functions as a unimolecular triple agonist targeting three distinct metabolic hormone pathways: GLP-1 (Glucagon-Like Peptide-1), GIP (Glucose-Dependent Insulinotropic Polypeptide), and GCGR (Glucagon Receptor).
This tri-agonist profile enables researchers to investigate complex metabolic interactions, synergistic glycemic control, enhanced energy expenditure, and liver fat accumulation dynamics in preclinical models.
Key Product Specifications
| Specification | Details |
| Product Name | GLP-3 R (Retatrutide Analog) |
| Quantity | 10mg per vial |
| Purity | $\ge 98\%$ (RP-HPLC & Mass Spectrometry verified) |
| Form | Sterile, lyophilized white powder |
| CAS Number | 2381089-83-2 |
| Molecular Formula | $\text{C}_{221}\text{H}_{342}\text{N}_{46}\text{O}_{68}$ |
| Molecular Weight | $4731.33\text{ g/mol}$ |
| Primary Target | Triple Agonist: GLP-1R / GIPR / GCGR |
Product Highlights & Scientific Context
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Triple Receptor Synergism: Simulates activation across GLP-1, GIP, and Glucagon receptors, providing a unique model to study simultaneous satiety signaling, insulin secretion, and glucagon-mediated hepatic lipid oxidation.
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Energy Expenditure Research: Glucagon receptor co-agonism provides a primary pathway for examining increased basal metabolic rates and thermogenesis alongside incretin-driven appetite suppression.
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Hepatic & Adipose Modulation: Extensively utilized in laboratory models investigating non-alcoholic fatty liver disease (NAFLD/MASH), lipid mobilization, and peripheral insulin sensitivity.
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Extended Half-Life Structure: Features a specialized C20 fatty diacid backbone extension to facilitate plasma albumin binding and support prolonged multi-day assay protocols.
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Sterile Lyophilized Format: Vacuum-sealed under nitrogen in borosilicate glass vials to ensure long-term secondary structure preservation.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C protected from light and moisture for up to 2 years. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with Bacteriostatic Water or sterile saline, store strictly at 2°C – 8°C and use within 28–30 days. Avoid repeated freeze-thaw cycles.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or cosmetic applications. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.
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