GLP-2 TZ (frequently designated in scientific vendor catalogs as research-grade Tirzepatide / dual GLP-1/GIP receptor agonist) is a synthetic 39-amino acid linear peptide engineered for advanced metabolic research. Formulated in high-purity 10mg and 30mg lyophilized formats, GLP-2 TZ functions as a dual agonist at both the Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) receptors.
This dual-receptor target allows researchers to study synergistic pathways involved in glucose-dependent insulin secretion, glucagon suppression, adipocyte lipid handling, and central satiety regulation.
Key Product Specifications
| Specification | Details |
| Product Name | GLP-2 TZ (Tirzepatide Analog) |
| Available Options | 10mg / 30mg per vial |
| Purity | $\ge 98\%$ (RP-HPLC & Mass Spectrometry verified) |
| Form | Sterile, lyophilized white powder |
| CAS Number | 2023788-19-2 |
| Molecular Formula | $\text{C}_{225}\text{H}_{348}\text{N}_{48}\text{O}_{68}$ |
| Molecular Weight | 4813.5 g/mol |
| Primary Target | Dual GIP and GLP-1 Receptor Agonist |
Product Highlights & Scientific Context
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Dual-Agonist Mechanism: Combines activation of GIP and GLP-1 receptors in a single molecule, providing a primary model for investigating receptor cross-talk and enhanced metabolic control over single-target incretins.
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Balanced Receptor Binding Profile: Engineered to demonstrate high binding affinity for GIP receptors alongside controlled potency at GLP-1 receptors.
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Lipid Metabolism & Satiety Modeling: Widely utilized in preclinical models investigating glucose homeostasis, delayed gastric emptying, peripheral insulin sensitivity, and adipose tissue remodeling.
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C20 Fatty Diacid Chain Extension: Features a specialized fatty acid diacid moiety that binds plasma albumin, extending the terminal half-life to approximately 5 days for multi-day assay protocols.
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Lyophilized Quality: Freeze-dried under nitrogen flush in sterile borosilicate glass vials to ensure optimal structural preservation and long shelf-life prior to reconstitution.
Storage & Handling Guidelines
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Lyophilized Powder: Store at -20°C or -80°C protected from light and moisture for up to 2 years. Short-term storage (under 30 days) at 2–8°C.
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Reconstituted Solution: Once reconstituted with Bacteriostatic Water or sterile saline, store strictly at 2°C – 8°C and use within 28–30 days. Avoid repeated freeze-thaw cycles.
Disclaimer & Research Notice:
This product is sold strictly for laboratory research and analytical purposes only. It is not intended for human consumption, medical diagnosis, therapeutic treatment, or cosmetic applications. All products should be handled by qualified scientific personnel using proper laboratory safety protocols.
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